What Doctors & Customers say...


"I have been using Proanthozone in allergic cases for over 10 years with some tremendous responses. The time between cortisone injections has been increased with every single animal."
- Clay Wilson, DVM of Beach Veterinary Clinic, FL

"I wish that I had taken a "before" picture, because "Jack" was such a miserable dog, constantly scratching and his coat and skin were a mess. He is a Black Lab with 1/8 Golden Retriever. Ever since he's been on Proanthozone Derm, I have noticed a significant change in his behavior! He used to be crazy with itching, but now he can focus on dog things like playing with the other 3 dogs, running through our peach orchard, or just relaxing like all dogs should be able to! Jack just got his summer cut today, which gave me a chance to see how his skin and undercoat are doing after being on Proanthozone Derm for almost a year! His skin used to be patchy from all the scratching and was really dry, scaly almost. Now he has hair over the patchy areas and his skin is a lot less dry. I really am glad to be using your product. You have a very happy client and patient and we appreciate what you do!"
- Mitzi DeMont, CVT & Jack-Jack Calvert of Grand Junction, CO

Jack



April 29, 2010 - John Harper, DVM of Texas reported using Proanthozone Derm in an old Lab/Retriever mix dog that had been to several veterinarians for constant scratching and a smelly coat. The dog was overweight, but no definitive health problems were uncovered. During administration of the first bottle of Proanthozone Derm, Dr. Harper says there was remarkable improvement. The dog stopped scratching and the bad odor was resolved. After 6 months on Proanthozone Derm, the itching and odor problems are still completely under control.


PROANTHOZONE® DERM

  • Skin, coat and allergy support formula for dogs
  • Bacon flavored chewable tablets

Indications: For the nutritional management of skin and coat problems, especially those associated with allergic dermatitis.

Main ingredients: Bioflavanol, Vitamin E, Vitamin A, Zinc, Alpha-Lipoic Acid, Omega-3 and Omega-6 Fatty Acids, Spirulina, and vegetarian flavoring

For years, veterinarians have used the original Proanthozone® formula in atopic dogs and have achieved positive results, often using it as an adjunct to more conventional therapies. Nonetheless, allergies and skin diseases have maintained their position at or near the top of the list of reasons why owners take their pets to the veterinarian. New Proanthozone® Derm includes ingredients for enhanced dermatologic use, such as omega-3 and omega-6 fatty acids, alpha-lipoic acid, and spirulina.

The basis of the formula is bioflavanol from grape seed extract. Polyphenolic antioxidants, such as bioflavanol, have been shown to help prevent mast cell degranulation and inhibit enzymes that promote histamine release, inflammation, and allergic reactions. Additional support comes from the antioxidant vitamins A and E and the antioxidant mineral zinc. Alpha-lipoic acid is a potent fat- and water-soluble antioxidant that is able to regenerate other antioxidants, such as vitamin E. Spirulina, a form of blue-green algae rich in beta carotene and vitamin E, enhances protective antibodies without enhancing those associated with allergies (IgE antibodies). Spirulina also has a direct antihistamine effect. Omega fatty acids are an important addition to the formula for controlling inflammation and supporting healthy cell membranes.

Frequently Asked Questions

Q. Is Proanthozone® Derm safe for cats?
A: We do not recommend Proanthozone Derm use in cats. Our formula contains alpha-lipoic acid, which can be toxic to cats. The amount we use is below the toxic level, but long-term effects at lower levels have not been determined.

Supporting Literature
1. Li WG, Zhang XY, Wu YJ, Tian X. Anti-inflammatory effect and mechanism of proanthocyanidins from grape seeds. Acta Pharmacol Sin. 2001 Dec; 22(12):1117-20
2. Chen S, Gong J, Liu F, Mohammed U. Naturally occurring polyphenolic antioxidants modulate IgE mediated mast cell activation. Immunology. 2000 Aug;100(4):471-80
3. Sen CK, Bagchi D. Regulation of inducible adhesion molecule expression in human endothelial cells by grape seed proanthocyanidin extract. Energy and Environmental Technologies Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, USA.
4. Serhan CN, Yacoubian S, Yang R. Anti-inflammatory and proresolving lipid mediators. Annu. Rev. Pathol. Mech. Dis. 2008;3:279-312.


What Doctors & Customers say...

"I am pleased overall with the results of Proanthozone Derm. The result I was not expecting, which I am happiest about, is that I have been able to lower the dose of NSAID in older, allergic dogs when I add Proanthozone Derm. Pepper, an 11 year old Lab mix, is the most notable. He now gets Zubrin every other day instead of every day." - Susan Colfer, DVM of Pet Kare Clinic, Steamboat Springs, CO

"I was asked to try Proanthozone Derm a veterinarian on my 2 year old Aussie. I have been using it for 2 months and I can already tell a difference in her coat and skin. She used to be on antibiotics regularly for itching and chewing raw spots. Now, since taking this product she has made it through the worst part of the season so far!"
- Heather, Britton Road Veterinary Clinic, OK


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